Год выпуска: 2008 Издательство: Страниц: 312 ISBN: 0849372895
Epigenetic changes are essential to normal development, but these changes can also cause problems including the disabling of genes that suppress tumors. At present, more than a dozen drugs that target epigenetic changes are in clinical trials. Epigenetics in Biology and Medicine offers a comprehensive overview of epigenetics, both in normal functions and disease states. This book presents contributions from international experts, addressing both theoretical and methodological issues. It discusses cell biology and the role of epigenetics in human, animal, and plant diseases. The text also covers DNA methylation inhibitors, histone modifications, and epigenomics, as well as the impact that diet has on epigenetic changes.