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Hypoxia on rat brain and therapeutic use of superoxide dismutase



Год выпуска: 2011
Автор: Manju Antony
Издательство: LAP Lambert Academic Publishing
Страниц: 164
ISBN: 9783845414416
Описание
This book deals with the study on the effect of isobaric hypoxic hypoxia (10%) on rat brain. Since literatures support generation of free radicals during post ischemic/hypoxic period, here hypoxia followed by reoxygenation is dealt with as the single problem. Subsequently, as brain shows regional variations in its function and metabolic activities an attempt was made to study effect of hypoxia- reoxygenation in five brain regions ie cerebrum, cerebellum, medulla, hippocampus and hypothalamus. The changes in the activities of antioxidant defense enzymes (superoxide dismutase, catalase and glutathione peroxidase), antioxidant GSH amount and lipid peroxidation levels in brain was analyzed biochemically accompanied by histochemical analysis of brain sections to detect ultrastructural changes in brain associated with hypoxia-reoxygenation. This book also deals with the use of liposomes entrapped with superoxide dismutase to circumvent this hypoxia associated pathological changes in brain....


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Елена
Добрый день, Юлия! Ещё раз благодарю Вас за консультации по творчеству Б.Пастернака. Преподаватель поставил за неё "отлично". Этот реферат добавил мне дополнительный балл при сдаче экзамена. Спасибо