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The effects of erythropoietin on telomerase in malignant cells



Год выпуска: 2014
Автор: Orit Uziel,Gil Kanfer and Meir Lahav
Издательство: LAP Lambert Academic Publishing
Страниц: 52
ISBN: 9783659515828
Описание
The study described in this book presents the effects of erythropoietin on Telomerase activity and regulation in malignant and non- malignant non-erythroid cells. Erythropoietin's exposure upregulates telomerase activity in a post translational level by the Lyn/SRC AKT axis. Inhibition of telomerase that shortens telomeres abolished that effect, suggesting that erythropoietin's treatment might be given with anti- telomerase compounds to minimize the upregulation of telomerase in the cancer cells.


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Юлия, 06.02
Спасибо большое за все!Наконец-то рук-ль работу одобрил!!!Было очень приятно с вами работать!