Role of Matrix metalloproteinase in Cancer development and progression
Год выпуска: 2013 Автор: D. Umadevi Издательство: LAP Lambert Academic Publishing Страниц: 60 ISBN: 9783659360558 Описание Colon cancer is the third most common form of cancer and the second leading cause of death among cancer patients. Therapeutic agents that can down regulate the expression of the enzyme matrix metalloproteinases (MMPs) in colorectal tumors may prove effective in the treatment of colorectal tumor, given the fact that this is highly metastatic in nature. Nitric oxide (NO), a free radical, plays major role in many signaling pathways takes the lead role in colon cancer progression. Emodin, a naturally occurring anthraquinone suppresses the NO mediated up regulation of matrix metalloproteinases. The study reveals that emodin can be targeted as an effective anti metastatic agent in NO induced tumor progression. The methodology involved detecting the non cytotoxic concentration of exogenous nitric oxide releaser (SNP) and emodin in WiDr cell line. Molecular level analysis of matrix metalloproteinase mRNA levels in SNP and emodin treated cells shows a clear correlation of the involvement of...
Похожие книги
Frank Ackerman, Neva R. Goodwin, Tufts University Global Development and Environment Institute. The Changing Nature of Work (Frontier Issues in Economic Thought, V. 4). – М.: , 0. – 0 с. Anne O. Krueger, Stanford University Center for Research on Economic Development and Po. Economic Policy Reforms and the Indian Economy. – М.: , 0. – 0 с. Jonathan M. Harris, Timothy Wise, Kevin Gallagher, Neva R. Goodwin, Tufts University Global Development and Environment Institute. A Survey of Sustainable Development: Social and Economic Dimensions (Frontier Issues in Economic Thought (Paperback)). – М.: , 0. – 0 с. Michael D. McGinnis, Bloomington Workshop in Political Theory and polic Indiana University. Polycentric Governance and Development: Readings from the Workshop in Political Theory and Policy Analysis (Institutional Analysis). – М.: , 0. – 0 с. Michael D. McGinnis, Bloomington Workshop in Political Theory and polic Indiana University. Polycentricity and Local Public Economies: Readings from the Workshop in Political Theory and Policy Analysis (Institutional Analysis). – М.: , 0. – 0 с. Dorothy J. Solinger, David A. Smith, Steven Topik, University of California Institute on Global Conflict and Cooperation. States and Sovereignty in the Global Economy. – М.: , 0. – 0 с. National Research Council and Institute of Medicine, Committee on the Health and Safety Implications of Child Labor. Protecting Youth at Work: Health, Safety, and Development of Working Children and Adolescents in the United States. – М.: , 0. – 0 с. Commission on Development and Environmen. Amazonia Without Myths. – М.: , 0. – 0 с. Frank Ackerman, Neva R. Goodwin, Laurie Doudherty, Frank N. Ackerman, Tufts University Global Development and Environment Institute. The Political Economy of Inequality (Frontier Issues in Economic Thought (Paperback)). – М.: , 0. – 0 с. International Symposium in Economic Theory and Econometrics 1996 univ, Carl Chiarella, Steve Keen, Robert Marks, Hermann Schnabl. Commerce, Complexity, and Evolution: Topics in Economics, Finance, Marketing, and Management : Proceedings of the Twelfth International Symposium in E ... Symposia in Economic Theory and Econometrics). – М.: , 0. – 0 с. Committee on Assessment of Resource Needs for Fuel Cell and Hydrogen Technologies, National Research. Transitions to Alternative Transportation Technologies--Plug-in Hybrid Electric Vehicles. – М.: , 2010. – 70 с. The Editors of Black Issues in Higher Education. The Unfinished Agenda of Brown v. Board of Education. – М.: , 2004. – 256 с. The Editors of Black Iissues in Higher Education (BIHE). The Unfinished Agenda of the Selma–Montgomery Voting Rights March. – М.: , 2005. – 240 с. ICAA (The Institute of Chartered Accountants in Australia). Auditing and Assurance Handbook 2010. – М.: , 2010. – 0 с. Inc. KT Solutions, KT Solutions has focused on what it takes to create efficient, professional multimedia training t KT Solutions specializes in the development of interactive multimedia training products for computer applications. Over the past decade. Beginning Windows NT Workstation 4.0 (Microsoft Windows NT). – М.: , . – с. Inc. KT Solutions, KT Solutions has focused on what it takes to create efficient, professional multimedia training t KT Solutions specializes in the development of interactive multimedia training products for computer applications. Over the past decade. Advanced Word for Office 97 (Microsoft Word 97). – М.: , . – с. In-Soo Han and Keun-Yeob Oh. LCD Industry in East Asia. – М.: LAP Lambert Academic Publishing, 2013. – 112 с. Образцы работ
Задайте свой вопрос по вашей теме
Контакты
Поделиться
Мы в социальных сетях
Реклама
Отзывы
Инна Спасибо, Марина!!! Огромное спасибо. Вы так порядочно относитесь к своей работе, сейчас это просто редкое качество. Вы просто молодец!!!