Год выпуска: 2012 Автор: Anisa Gumerova,Andrey Kiassov and Sayar Abdulkhakov Издательство: LAP Lambert Academic Publishing Страниц: 128 ISBN: 9783659122071
Описание
The central problem of modern hepatology is identification of a regional hepatic stem cell. Necessity of solving this problem is dictated by considerable prevalence of chronic liver diseases, insufficient efficiency of existing methods of their treatment, and as a consequence – by high frequency of liver fibrosis and cirrhosis development as an outcome of these diseases. Liver transplantation becomes the only possible method of treatment in these cases. However existing deficiency of donor organs, long waiting lists, high cost of transplantation and necessity of subsequent immunosuppression dictate necessity of search of new approaches in therapy of this group of diseases. Identification of the hepatic stem cell would allow development of essentially new methods in treatment of chronic liver diseases based on stimulation of autologous hepatic stem cells and application of cellular therapy including genetically modified stem cells. Therefore the aim of our research was to study...
