Год выпуска: 2014 Автор: Hong Kang Издательство: LAP Lambert Academic Publishing Страниц: 168 ISBN: 9783659278112
Описание
This book explores the applications of plasmonic gold nanorods (GNRs) in early cancer diagnostics and treatment by engineering the light focusing properties. On account of polarisation-dependent excitation efficiency of GNRs and their three-dimensionally random orientations, radially polarised beams are advantageous over linearly polarised beams because they can generate focal fields with the similar strength in three dimensions. Meanwhile, the energy density is studied to provide comprehensive understanding of light-matter interaction. Investigations into two-photon excited fluorescence (TPEF) imaging of gold nanorods doped in nanocomposite films are conducted by applying different values of numerical aperture (NA) and annular obstruction sizes under linear and radial polarisation illumination, which shows that the radially polarised beam can produce stronger TPEF imaging in the presence of high NA. The effectiveness of the radial polarisation is further confirmed by the detection...