Population balance modelling of non-native protein aggregation Год выпуска: 2012Автор: Peter GrancicИздательство: LAP Lambert Academic PublishingСтраниц: 108ISBN: 9783659212031Описание A comprehensive modelling methodology for analysis of the kinetics of non-native protein aggregation based on general population balance model within the Extended Lumry-Eyring framework is presented. The population balance model is formulated in terms of key parameters, describing relative importance of (un)folding and aggregation kinetics of a protein in diffusion-driven conditions. Both the analytical and numerical solution provide a detailed insight on the intrinsic aggregation kinetics via time-dependent evolution of a variety of experimentally measurable quantities.
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Анастасия, 18.12 Спасибо большое, я вижу, что работа отличная!
