Год выпуска: 2012 Автор: Soram Ibomcha Singh Издательство: LAP Lambert Academic Publishing Страниц: 104 ISBN: 9783659172380
Описание
Noble chiral organic (mixed) phosphoramidates contain both C-O-P and C-N-P linkages and are found to possess great biological significance as intermediates in metabolism. Moreover, new promising phosphoramidate prodrugs have been developed recently. This book therefore, provides new milestone towards synthesis of chiral organic phosphoramidates and their hydrolytic degradation studies. The different chapters have been assigned to facilitate an easier understanding of the following titles: •Introduction to the recent investigations in phosphoramidates •Synthesis of chiral phosphoramidates •Characterization by various spectroscopic methods. Kinetic study/in vitro hydrolytic reactivity study. With its clear and systematic presentation, this book will pave great beneficial understanding to researchers, scholars and students at large.
