Год выпуска: 2012 Автор: Navneet Kumar Yadav Издательство: LAP Lambert Academic Publishing Страниц: 52 ISBN: 9783846549544
Описание
The objective of homology modeling is to build a 3D model for a protein of which the structure is unknown (the target) on the basis of sequence similarity to proteins of known structure (the templates). Computational tools provide researchers to understand physic-chemical and structural properties of proteins . A large number of computational tools are available from different sources for making predictions regarding the identification and structure prediction of proteins . The major drawbacks of experimental methods that have been used to characterize the proteins of various organisms are the time frame involved, high cost and the fact that these methods are not amenable to high throughput techniques. In silico approaches provide a viable solution to these problems. The amino acids sequence provides most of the information required for determining and characterizing the molecule’s function, physical and chemical properties. Computationally based characterization of the features...
