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Alpha-1 Proteinase Inhibitor in Action: Roles and Mechanistic Insights



Год выпуска: 2012
Автор: Vivek Gupta and Veer Bala Gupta
Издательство: LAP Lambert Academic Publishing
Страниц: 200
ISBN: 9783659261770
Описание
Alpha 1 proteinase inhibitor, the archetypal member of the serpin superfamily is an acute phase protein and protects pulmonary tissues from gtatuitous elastase digestion and inhibits neutrophil elatase at sites of inflammation. In this book we have explained the structure function relationships of alpha 1 proteinase inhibitor. A detailed biochemical characterization and mechanism of multiple protease inhibition elucidated. Further, alpha 1 proteinase inhibitor interactions with negatively charged heparin have been localised in terms of specific residues involved and investigated in terms of both activation as well as conformational changes.


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Екатерина, 25.04
Сегодня встречалась с руководителем по поводу диплома. С антиплагиатом всё хорошо, работа прошла.