Effects of microtubule-interfering agents on AhR signalling Год выпуска: 2012Автор: Radim VrzalИздательство: LAP Lambert Academic PublishingСтраниц: 100ISBN: 9783659180224Описание Microtubule-interfering agents are compounds which affect microtubules network. They found use in cancer therapy (vinblastine, paclitaxel) or as anti-inflammatory agents (colchicine). Present work focuses on the effect of these compounds in signalling of aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor regulating expression of many genes, some of them being involved in biotransformation of carcinogens.
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