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Computational methods for screening and engineering enzyme properties



Год выпуска: 2013
Автор: Lorena Knapic
Издательство: LAP Lambert Academic Publishing
Страниц: 180
ISBN: 9783659346255
Описание
Biocatalysis is an excellent alternative to classical chemical catalysis offering environmentally benign manufacturing, sustainable development and green chemistry. Understanding enzyme properties at an atomic level is the major advantage offered by computational techniques and the only route for rational engineering of enzyme properties. This work describes specifically developed state of the art methodologies that deal with enzyme reaction promiscuity and substrate promiscuity phenomena. An innovative tool for in silico enzyme evolution and screening has also been developed and its assembly from scratch and validation are thoroughly described. The existing drawbacks of industrial application of enzymes need to be overcome by a combined effort of scientists in which computational chemists and biologists have much to contribute.


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Ирина, 16.09
Я уже говорила Вам спасибо за курсовую, которую Вы для меня сделали. Вчера я узнала оценку - 21 балл, при максимуме - 25. Это пять! Я думаю, Вам приятно будет узнать это. Еще раз огромное Вам спасибо. И надеюсь, что Вы мне согласитесь еще раз помочь, если в этом возникнет необходимость