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Antibacterial and Antifungal Lectins from Leguminous Plants



Год выпуска: 2012
Автор: RABIA HAMID,Ms Sakeena and AKBAR MASOOD
Издательство: LAP Lambert Academic Publishing
Страниц: 140
ISBN: 9783846581568
Описание
Lectins are carbohydrate-binding proteins of non-immune origin that agglutinate cells or precipitate glycoconjugates.Based on evolutionary and structural relatedness, seven lectin families have been distinguished, of which legume lectins are the best characterized. Lectins typically constitute a large fraction of the total protein in most leguminous seeds and plant storage tissues where they play an important role in several defense mechanisms. A lectin from the seeds of Indigofera heterantha, member of family leguminosae was isolated, purified, partially characterized and its antimicrobial activity evaluated. The lectin is a homotetramer with a molecular weight of about 70 KDa. The lectin shows a reasonable temperature stability and is stable in the pH range of 2-9. It demonstrates a remarkable antibacterial activity against E.coli, K.pneumonia, S.aureus, and B.subtilis and also inhibits the growth of phytopathogens Aspergillis niger, Aspergillis oryzie and Fusarium oxysporum. These...


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