Evaluation of New Bicyclic Lactone ''Michelianone'' Год выпуска: 2011Автор: VICHITRA KAUSHIK,Ratan Lal Khosa and Versha ParchaИздательство: LAP Lambert Academic PublishingСтраниц: 84ISBN: 9783843353090Описание A novel bicyclic lactone ''Michelianone'' (P4) has been isolated from anti-inflammatory activity guided fractionation of chloroform extract of Michelia oblonga leaf with a gradient of ethyl acetate in petroleum ether. Further P4 was screened for anti- inflammatory activity on carrageenan and dextran induced inflammation model in rats at the dose level of 50 mg/kg body weight. Treatment of inflammed rats with P4 has showed significant reduction in inflammation caused by carrageenan (P<0.01) and dextran (P<0.05). Hence P4 can be considered as the principle component responsible for the anti- inflammatory activity for Michelia oblonga leaf. The characterization of P4 was done by spectral studies like IR, 1H-NMR, 13C-NMR & Mass Spectroscopy. On the basis of spectral studies the structure of P4 has been elucidated as bicyclic lactone. This is a novel bicyclic lactone isolated from the leaf of M. oblonga for the first time and given a trivial name Michelianone.
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Olga Огромное Вам спасибо за рефераты, я сегодня их забрала и прочитала, в понедельник поедем сдавать в экстернат. Не могу не сказать Вам, что Вы очень талантливый и тонкий человек. Я хорошо знаю, что образование, каким бы качественным оно не было, не даёт возможности безошибочно почувствовать поставленную задачу. Высокое качество Ваших работ бесспорно, однако меня больше всего поразила точность и артистичность не просто реализации цели и задач исследования, а исполнения специалистСКОЙ по духу работы: в нашем случае это не просто рефераты на заданную тему, а рефераты совершенно определённого качественно (в смысле возраста, уровня образования и т.п.) специалиста. Выражаю Вам своё восхищение, надеюсь на дальнейшее сотрудничество.
