Once a day mucoadhesive formulation of gliclazide
Год выпуска: 2013 Автор: Purnima Tripathi,Udhumansha Ubaidulla and Sonia Pandey Издательство: LAP Lambert Academic Publishing Страниц: 116 ISBN: 9783659388668 Описание In this research work an attempt was made to prepare once a day formulation of gliclazide. The purpose was achieved by making mucoadhesive microcapsules of gliclazide. A combination of polymers, sodium alginate, sodium Carboxy Methyl Cellulose, hydoxy propyl methyl cellulose and carbopol 934P was utilized for this purpose. The formulation was prepared and optimized and evaluated for in-vitro and in-vivo performance. The results obtained were very satisfactory.
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