Analgesic and Antiinflammatory activity of Spinacia oleracea Linn
Год выпуска: 2013 Автор: Tahmina Yasmin,Sabrina Mahjabeen and Jinat Tasnim Издательство: LAP Lambert Academic Publishing Страниц: 96 ISBN: 9783659406904 Описание The purpose of the present investigation was to evaluate the possible Analgesic, Anti-Inflammatory activities of Spinacia olearacea Linn.The ethanolic (80%) extract elicited a highly significant (p<0.001) analgesic activity on hot plate method, acetic acid induced writhing test.In the hot plate method, the extract increased the reaction time of heat sensation to 73.3 %and 92.8% at the doses of 250 and 500 mg/kg BW respectively while that of the standard drug was 97.3% at the 3rd hour of study. In acetic acid induced writhing test, the percent inhibition of writhing response by the extract was 39.23% and 64.62% at 250 and 500 mg/kg doses respectively (p<0.001) while the standard Ketorolac inhibition was 66%.The oral administration of the extract significantly (p...
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