Chitosan : A natural solubility enhancer for simvastatin Год выпуска: 2012Автор: Pattewar Seema,Deepak Patil and Ravindra JadhavИздательство: LAP Lambert Academic PublishingСтраниц: 84ISBN: 9783659288418Описание The enhancement of the oral bioavailability is currently one of the greatest challenges in the development of poorly water soluble drugs. The main objective of work to enhance solubility of Simvastatin (SIM) by use of natural polymer, chitosan (CHI) to produce cost effective formulation.Physical mixture, co-grinding method, spray drying method are compared.Co-grinding method applied for preparation of drug polymer complex and compared with the solubility and dissolution of marketed preparation.
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N N Марина, спасибо Вам большое за диплом после вашего сопровождения. Всё благополучно завершилось. Материал произвёл самое благоприятное впечатление.
