Год выпуска: 2013 Автор: Ishan Ghai and Hema Chaudhary Издательство: LAP Lambert Academic Publishing Страниц: 56 ISBN: 9783659317200
Описание
The basic fundamental of Trans Dermal Drug delivery system is to deliver the right amount of dosage, at the right time to the right target. Thus increased patient compliance with Avoidance of the first pass metabolism and Controlled and consistent administration of the drug. Targeting the skin for drug delivery Via can be possible by delivering the drug moiety through the surface of the skin, Through the skin (subcutaneous) and Direct delivery of drug molecule, into the systemic circulation. Drug penetration pathway Sweat ducts Hair follicles Sebaceous glands helps drug moiety to transfer directly across the stratum Corneum. Vesicular Approach for Modulation of Transdermal Penetration Colloidal particles formed as a concentric bio molecular layer that are capable of encapsulating drugs and are composed of the lipids, that are similar to the lipids present in the stratum corneum. Ethosomes Elastic vesicles, primarily composed of phospholipids Contains a high...
