Год выпуска: 2013 Автор: Arumugam Madeswaran Издательство: LAP Lambert Academic Publishing Страниц: 140 ISBN: 9783659370168
Описание
The book entitled “Discovery of potential phosphodiesterase inhibitors using in silico docking studies”. Molecular docking studies are gaining importance in the new drug discovery process as a tool for high-throughput screening. This book deals with the evaluation of phosphodiesterase inhibitory activity of flavonoids using in silico docking studies. In this perspective, various flavonoids were analyzed for their anti-inflammatory activity, especially in inflammatory pulmonary diseases such as asthma, COPD, and rhinitis. This book highlights the information about the structural models of the flavonoids in the phosphodiesterase (PDE4) binding sites, which may facilitate further development of more potent phosphodiesterase inhibitory agents. This book will be very useful to the undergraduate, postgraduate and Ph. D., students of Pharmacists, Pharmacologists and Medicinal Chemists. Bioinformatics researchers will be interested in this book. It is a basic handbook to know about drug...
