ZAP-70 phosphorylation and other prognostic factors in B-CLL patients Год выпуска: 2013Автор: Aaron MarambaИздательство: LAP Lambert Academic PublishingСтраниц: 304ISBN: 9783659448188Описание This book is the culmination of a major three and half-years' work on B-chronic lymphocytic leukaemia (B-CLL) to stratify its prognostication. It represents a comprehensive analysis of various prognostic factors in adult B-CLL patients. The book is a fantastic resource and could be used by a range of professionals. Its main focus is on the laboratory diagnosis of B-CLL using basic methods as well as flow cytometry. Flow cytometry is further employed to demonstrate that ZAP-70 positive cells are more responsive to signals derived from their surounding environment, such as stromal cell-derived factor 1-alpha (SDF-1a).
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