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REVERSIBLE SYSTOLIC DYSFUNCTION IN CHRONIC KIDNEY DISEASE



Год выпуска: 2010
Автор: Srilakshmi Adhyapak and Shamanna S.Iyengar
Издательство: LAP Lambert Academic Publishing
Страниц: 64
ISBN: 9783843384049
Описание
There is a hypothesis that a subgroup of patients with reversal of systolic dysfunction following hemodialysis have fluid overload. However, the underlying pathology has not been understood in those patients without significant fluid overload. Inflammatory markers have been found to be raised in chronic kidney disease, which prompts the theory for an underlying inflammatory pathology as a cause of reversible cardiac dysfunction in this group of patients. We studied 52 patients with chronic kidney disease. There were 29 patients with systolic dysfunction. Twenty three patients with preserved systolic function, had diastolic dysfunction. Of the 29 patients with systolic dysfunction, 10 patients had significant improvement in NYHA functional class, left ventricular dimensions, left ventricular ejection fraction . None of the patients had significant changes in dry weight. These patients had the highest baseline serum levels of troponin I which decreased...


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