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Synthesis and Reactions of Some New s-Triazole Derivatives



Год выпуска: 2013
Автор: Bahgat Hussein
Издательство: LAP Lambert Academic Publishing
Страниц: 176
ISBN: 9783659385285
Описание
Various 1,2,4-triazoles found extensive investigations due to their useful application in different areas of biological activity and as industrial intermediates such as antiasthmatic, antiviral, antifungal, antimicrobial, antibacterial, insecticidal, amoebicidal, hypnotic,cytotoxic and hypotensive activities. This moiety was also found in potent agonist and antagonist receptor ligands, in HIV-1 protease inhibitors and in thrombin inhibitors. Along with these significant pharmaceutical uses, 1,2,4-triazole derivatives are effectively used in polymers, dyestuff, photographic chemicals and agricultural chemicals. In view of these findings and in continuation of our work in the same field we provide in this book, the synthesis of some new s-triazole derivatives and tested for antibacterial activity.


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