Washout Rate of Tc-99m MIBI in Bone and Soft-tissue Sarcomas
Год выпуска: 2014 Автор: Muhammad Sohaib Издательство: LAP Lambert Academic Publishing Страниц: 80 ISBN: 9783659580505 Описание Neoadjuvant therapy is employed before the primary treatment of sarcomas. It is not uncommon that it fails due to multi-drug resistance gene causing unnecessary delays in surgery. Tc-99m MIBI, a radiopharmaceutical, is taken-up in these tumours. Being substrate of P-glycoprotein (Pgp), its washout from the malignant tissue may predict the response of sarcoma to neoadjuvant therapy. This book presents the author’s experience of in-vivo quantitative estimation of the washout rates of Tc-99m MIBI from nuclear medicine scans of various bone and soft-tissue sarcomas. These rates were then assessed for their ability to predict the effectiveness of neoadjuvant therapy initiated afterwards.
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Марианна Юлия. огромное спасибо! Защитилась на отлично, работа после вашего сопровождения комиссии понравилась.