Год выпуска: 2012 Автор: Menan Rabie and Hisham Ramy Издательство: LAP Lambert Academic Publishing Страниц: 140 ISBN: 9783659157844
Описание
The results of this study indicate that (Neurological Soft Signs) NSS and Cognitive Dysfunction) CD are prevalent in bipolar probands and their first-degree relatives, though significantly more in affected subjects. This suggests that NSS and CD could be considered as trait and/or scar markers and lends support to the theory that bipolar disorder may be a neurodevelopmental disorder. Clinical implications of these findings are discussed and a biological model of bipolar disorder is suggested. The study addressed the presence of these abnormalities in 35 euthymic bipolar subjects, 85 healthy first-degree relatives, and 50 healthy controls, using the Neurological Evaluation Scale, Subtests of Wechsler Adult Intelligence test, Verbal Paired Associates, Digit Span and Visual Memory Span of Wechsler Memory Scale-Revised and Wisconsin Card Sorting Test. NSS were more prevalent in bipolar patients than healthy relatives and control, but also significantly more in healthy relatives than...
