Replicative Cessation & DNA Damage in Human Fibroblast under Stress Год выпуска: 2011Автор: Sahar Khalil,Gehad Hammouda and Somaya HosnyИздательство: LAP Lambert Academic PublishingСтраниц: 204ISBN: 9783846553268Описание Aging can be viewed partly as a degenerative process dictated by free radical reactions. Human diploid fibroblasts (HDFs) lose the capacity to proliferate and enter a state termed replicative senescence after a finite number of population doublings in vitro. Presenescent human fibroblasts, when treated with a sub-lethal dose of H2O2, enter long term growth arrest resembling replicative senescence. H2O2 induced growth arrest; p53 protein expression and the effect of vitamin C as an antioxidant were determined in this study.
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Екатерина, 10.05 Я все посмотрела,большое спасибо! Именно так и просил преподаватель.
