Год выпуска: 2014 Автор: Zakia Sultana Sathi and Md. Mahfuj Alam Siddeq Издательство: LAP Lambert Academic Publishing Страниц: 88 ISBN: 9783659572388
Описание
Dillenia indica Linn, commonly known as Chalta, is abundantly available almost all over Bangladesh. The present study was carried out to evaluate the anti-diabetic and anti-hyperlipidemic properties of Dillenia indica on type 2 diabetic model rats. A single intraperitoneal (i.p) dose of chloroform fraction (200 mg/ kg body weight) of methanol extract of Dillenia indica fruit significantly reduced fasting blood glucose (FBG) level on alloxan induced diabetic rats. The most significant reduction of FBG level (65%) after 50 hour of administration. This effect almost similar to that of standard drug metformin (150 mg/kg b.w.). In alloxan induced diabetic rat, the total cholesterol and serum triglyceride levels were increased by 49 and 41%, respectively. Chloroform fraction of fruit also reduced the total cholesterol and serum triglyceride level 60 and 55%, respectively on alloxan induced rat. On the hand, CHCl3 fraction of D. indica bark at early phase reduced the blood glucose level and...
