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Genotoxicity Of Aliskiren In The Bone Marrow And Germ Cells Of Mice



Год выпуска: 2014
Автор: Rina Desai Tripathi,I.S. Anand and C. N. Patel
Издательство: LAP Lambert Academic Publishing
Страниц: 92
ISBN: 9783659103742
Описание
As there is a need to combat human diseases, many drugs are being used in the medical field. Though these drugs control the disease, when used in higher doses they may be toxic to the genetic system of human beings. Antihypertensive drugs are the most widely prescribed medications in the world. The duration of the pharmacological treatment of hypertension may last for decades and, therefore, patients are exposed to prolonged contact with these drugs. Long-term treatments require documentation of long-term safety and efficacy, including sensitive indices of genotoxic damage. Important part of prescription for hypertensive patients is Aliskiren, the third-generation renin inhibitor, prescribe for patient of hypertension. However the present topic is to understand the possible genotoxic effects of its long term use. This scientific information makes the people aware to utilize drug in preventive dose regimen and may be of interest to many pharmaceutical companies, bulk pharmaceuticals...


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