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Relationship of TNF-? with insulin sensitivity in T2DM subjects


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Год выпуска: 2012
Автор: Ayesha Bilal,TASNIM FARASAT and Zubia Bilal
Издательство: LAP Lambert Academic Publishing
Страниц: 120
ISBN: 9783659177217
Описание
 Diabetes mellitus is a multifactorial disorder. Cytokines secreted by the monocyte-macrophage system play a key role in the pathogenesis of type 2 diabetes. Pro-inflammatory cytokine TNF-? is believed to have an important role in the progression of diabetes. The present study was conducted to assess the level of TNF-? and to find its relationship with insulin sensitivity and other indicators of metabolic syndrome among newly diagnosed type II diabetic subjects. 100 diabetic subjects (age; 48.63±0.92, BMI; 28.51±0.52) were included in the study. Four groups were made on the basis of BMI as normal weight, overweight, moderately obese, severely obese subjects. Different demographic parameters as age, BMI, B.P, personal history and socioeconomic status were recorded. Fasting glucose, random glucose, HbA1c and lipid profile were analyzed by chemistry analyzer. Serum insulin and plasma TNF-? levels were assessed by ELISA. Insulin sensitivity and insulin resistance was calculated. ANOVA...

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Марина
Марина, материалы дошли, всё открылось. Так что всё замечательно. БОЛЬШОЕ СПАСИБО!!! Было приятно с вами работать (вернее это вы за нас работали, но всё же...) Спасибо.