Год выпуска: 2013 Автор: Pravina Piste,Shubhangi Waghamale and Maruti Kanase Издательство: LAP Lambert Academic Publishing Страниц: 124 ISBN: 9783659484902
Описание
Triazole, oxadiazole and thiadiazole a five membered heterocyclic nucleus has attracted a wide attention of the Chemist in search for the new therapeutic molecules. This heterocyclic nucleus play vital role in biological and Medicinal field. This diversity in the biological response profile has attracted the attention of many researchers to explore these Skeletons to its multiple potential against several activities. So we have developed a A series of different Triazole and Oxadiazole derivatives by adopting Green approach. Chapter-I describes a brief summary of the pharmacological activities of Triazole ,Oxadiazole and Thiadiazole system and highlights some examples of recent drug containing this moieties.Chapter-II describes Different synthetic methods.Further Synthesis of different 6-Methyl-4-aryl-5-(5-aryl-1,3,4-oxadiazole-2-yl)-1,2,3,4-tetrahydro pyrimidine-2- (1H)-one / thione in Chapter-III. While Chapter-IV includes A series of...