Design selective glutamate dehydrogenase inhibitors? Год выпуска: 2011Автор: Yunbo SongИздательство: LAP Lambert Academic PublishingСтраниц: 132ISBN: 9783844301588Описание Plasmodium falciparum glutamate dehydrogenase (GDH) is an attractive target for the rational development of new antimalarial drugs. Enzyme Kinetics assays and molecular modelling technology were used to measure inhibition effects for some ligands on two different GDHs. The study presented in this work provided a base line for future explorations and discoveries of the inhibition selectivity between Plasmodium and human GDH based on bacterial and mammalian animal GDH.
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Настя Добрый вечер, Мария! Спасибо большое за вашу помощь! Получила отлично за курсовую. Замечаний больших нет, очень понравился анализ произведения. Хотела бы спросить, можно ли будет рассчитывать на вашу помощь в следующем году при сопровождении диплома? Я бы очень хотела этого. Конечно, все станет ясно с темой не раньше осени, но, я думаю, она будет связана с темой этой курсовой. В любом случае, надеюсь на дальнейшее сотрудничество
