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Levels of Some Heavy Metals in Human Blood in Zaria, Nigeria



Год выпуска: 2012
Автор: Aminu Musa
Издательство: LAP Lambert Academic Publishing
Страниц: 264
ISBN: 9783659104411
Описание
Heavy metals are widely dispersed in the environment and tend to accumulate in select tissues of the human body resulting in potential toxicity. They have also been reported to form complexes with certain classes of drugs, which may affect the availability, and consequently the activity of such drugs.High levels of heavy metals in environmental and food samples around Zaria, Nigeria have been reported. Hence, this study determined the concentrations of Cd, Cr, Mn, and Zn in blood of humans in Zaria and their effects on the availability and activity of chloramphenicol, ciprofloxacin and metronidazole. Results obtained show higher levels of the metals in occupationally exposed individuals compared to the general population. The in vitro availability of chloramphenicol, ciprofloxacin and metronidazole were significantly (P > 0.05) decreased when interacted with all the metals. The antimicrobial actions of chloramphenicol and metronidazole when interacted with the metals indicated that in...


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Галина
Юля,здравствуйте! Курсовые работы после вашего сопровождения защитили на 5. Спасибо Вам огромное! Правда гоняли как бобиков- пришлось выкручиваться кто как мог!