Evaluation of New Lupane-Type Triterpene ''Diospyrosonate''
Год выпуска: 2011 Автор: VICHITRA KAUSHIK,Versha Parcha and Ratan Lal Khosa Издательство: LAP Lambert Academic Publishing Страниц: 84 ISBN: 9783844301045 Описание A novel lupane-type triterpene ''Diospyrosonate'' (P1) has been isolated from anti-inflammatory activity guided fractionation of petroleum ether extract precipitate of Diospyros malabarica stem bark with a gradient of ethyl acetate in petroleum ether. Further P1 was screened for anti- inflammatory activity on carrageenan and dextran induced inflammation model in rats at the dose level of 50 mg/kg body weight. Treatment of inflammed rats with P1 has showed significant reduction in inflammation caused by carrageenan (P<0.05) and dextran (P...
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