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Photolytic Degradation of Tenaxit®(Flupentixol-Melitracen Combination)



Год выпуска: 2014
Автор: Nigar Sultana,Nakib Ibne Omar and Md. Shahidul Islam
Издательство: LAP Lambert Academic Publishing
Страниц: 132
ISBN: 9783659571152
Описание
The aim of this research work is to the determination of photolytic degradation of the Tenaxit®, product of Incepta Pharmaceuticals Ltd., Bangladesh. Each tablet contains flupentixol INN 0.5 mg (as di-hydrochloride) and melitracen INN 10 mg (as di-hydrochloride). By conducting various type of physical, chemical and instrumental tests were done to determine whether the product is photo sensitive or not in various conditions (control, direct sunlight, normal light in the room, 25watt and 40watt light condition). Physical tests were performed according to the specification of official pharmacopoeia for evaluation of hardness, thickness, weight variation, friability of the Tenaxit® tablets from same batch. Finally, the sample was prepared for the UV-Spectroscopy measurement and absorbance of prepared sample was measured. It was observed that the potency of Tenaxit® was decreased gradually in various conditions after light exposure. So it can be said that the Tenaxit® containing...


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Михаил, 24.04
Добрый вечер! Получил 5 по курсовой! Большое спасибо!