Год выпуска: 2014 Автор: Jayaraj Chinchali and Basappa Kaliwal Издательство: LAP Lambert Academic Publishing Страниц: 152 ISBN: 9783659640858
Описание
Skin, a major environmental interface for the body, is accidentally or occupationally exposed to a number of chemical mutagens and carcinogens. Skin cancer accounts for 30% of all diagnosed cancers in the world. The evaluation of anticarcinogenic activity of Clerodendrum serratum leaf extract on DMBA induced skin carcinogenesis in swiss albino mice revealed that there was decrease in the body and organs weight, affected biochemical contents, dehydrogenases and phosphatases activities and oxidative stress parameters of liver, kidney and testes of mice. Amelioration in the above mentioned parameters was observed on treatment with methanolic leaf extract of Clerodendrum serratum, indicating its anticarcinogenic potential. The inferences drawn from the study revealed that the methanolic leaf extract of Clerodendrum serratum recovered the biochemical contents, dehydrogenases and phosphatases activity and oxidative stress parameters of liver, kidney and testes of mice. The presence of major...
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